4-CHLORO-D-PHENYLALANINE HYDROCHLORIDE
4-chloro-d-phenylalanine hydrochloride
CAS: 147065-05-2
Molecular Formula: C9H11Cl2NO2
4-CHLORO-D-PHENYLALANINE HYDROCHLORIDE - Names and Identifiers
4-CHLORO-D-PHENYLALANINE HYDROCHLORIDE - Physico-chemical Properties
| Molecular Formula | C9H11Cl2NO2 |
| Molar Mass | 236.1 |
| Melting Point | 235 °C |
| Storage Condition | Room Temprature |
| Refractive Index | 10 ° (C=1, H2O) |
4-CHLORO-D-PHENYLALANINE HYDROCHLORIDE - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R43 - May cause sensitization by skin contact |
| Safety Description | S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 |
4-CHLORO-D-PHENYLALANINE HYDROCHLORIDE - Introduction
4-chroo-d-phenylalanine hydrochloride is a chemical substance that has the following properties:
1. Appearance: usually white to light yellow crystalline powder.
2. Solubility: soluble in water, insoluble in organic solvents.
3. Stability: relatively stable at room temperature.
4. Ph value: usually in the neutral to alkaline range.
5. Optical rotation: It has optical rotation and can rotate polarized light.
The main uses of 4-chroo-d-phenylalanine hydrochloride include:
1. Chiral ligands: can be used as chiral ligands for the synthesis of drugs and Chiral separation in organic synthesis.
2. Chemical synthesis: As a synthetic intermediate of chiral xanthone, it participates in the preparation of drugs and pesticides.
Method:
The preparation method of 4-chroo-d-phenylalanine hydrochloride usually involves the following steps:
1. Phenylalanine reacts with carbon tetrachloride to generate chiral phenylpropyl chloride.
2. The generated phenylpropyl chloride is reacted with hydrochloric acid to obtain 4-chloro-d-phenylpropyl chloride.
3.4-chloro-D-phenylpropyl chloride is reacted with sodium chloride to generate 4-chloro-D-phenylpropyl sodium chloride.
4. 4-chloro-d-phenylpropyl sodium chloride is reacted with hydrochloric acid to generate 4-chloro-d-phenylalanine hydrochloride.
Safety Information:
The following safety precautions should be taken when using 4-chroo-d-phenylalanine hydrochloride:
1. Use to maintain good ventilation conditions, avoid inhalation of powder or solution.
2. Avoid contact with skin and eyes, avoid swallowing.
3. Appropriate personal protective equipment, such as lab gloves, goggles and protective clothing, must be worn.
4. Try to avoid the release of the substance into the environment, and handle and dispose of it in accordance with local regulations.
5. Storage should be away from fire and oxidant, stored in a dry, cool, well-ventilated place.
1. Appearance: usually white to light yellow crystalline powder.
2. Solubility: soluble in water, insoluble in organic solvents.
3. Stability: relatively stable at room temperature.
4. Ph value: usually in the neutral to alkaline range.
5. Optical rotation: It has optical rotation and can rotate polarized light.
The main uses of 4-chroo-d-phenylalanine hydrochloride include:
1. Chiral ligands: can be used as chiral ligands for the synthesis of drugs and Chiral separation in organic synthesis.
2. Chemical synthesis: As a synthetic intermediate of chiral xanthone, it participates in the preparation of drugs and pesticides.
Method:
The preparation method of 4-chroo-d-phenylalanine hydrochloride usually involves the following steps:
1. Phenylalanine reacts with carbon tetrachloride to generate chiral phenylpropyl chloride.
2. The generated phenylpropyl chloride is reacted with hydrochloric acid to obtain 4-chloro-d-phenylpropyl chloride.
3.4-chloro-D-phenylpropyl chloride is reacted with sodium chloride to generate 4-chloro-D-phenylpropyl sodium chloride.
4. 4-chloro-d-phenylpropyl sodium chloride is reacted with hydrochloric acid to generate 4-chloro-d-phenylalanine hydrochloride.
Safety Information:
The following safety precautions should be taken when using 4-chroo-d-phenylalanine hydrochloride:
1. Use to maintain good ventilation conditions, avoid inhalation of powder or solution.
2. Avoid contact with skin and eyes, avoid swallowing.
3. Appropriate personal protective equipment, such as lab gloves, goggles and protective clothing, must be worn.
4. Try to avoid the release of the substance into the environment, and handle and dispose of it in accordance with local regulations.
5. Storage should be away from fire and oxidant, stored in a dry, cool, well-ventilated place.
Last Update：2024-04-09 19:05:46
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